Search Result
Results for "
hydrogen peroxide
" in MedChemExpress (MCE) Product Catalog:
5
Biochemical Assay Reagents
Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-W402148
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ROS Kinase
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Others
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10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide .
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- HY-129064
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SOD
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SOD
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Inflammation/Immunology
Cancer
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Superoxide dismutase, Porcine erythrocytes (SOD) is the only antioxidant enzyme that scavenges the superoxide anion by converting this free radical to oxygen and hydrogen peroxide, thus preventing peroxynitrite production and further damage. Superoxide dismutase, Porcine erythrocytes is extensively researched and used in anti-inflammatory, antitumor, radiation protection, and antisenility applications .
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- HY-W455884
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Others
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Others
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3,5-Dichloro-2-hydroxybenzenesulfonic acid is used in conjunction with Ampyrone (HY-B1398) (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantification of peroxidase in coupled enzymatic reactions. 3,5-Dichloro-2-hydroxybenzenesulfonic acid is used to measure hydrogen peroxide production in conjunction with peroxidase .
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- HY-N3563
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Others
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Neurological Disease
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Celaphanol A is a diterpene that can be isolated from the root bark of Celastrus orbiculatus. Celaphanol A shows neuroprotective effect against a hydrogen peroxide-induced cytotoxicity in PC12 cells .
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- HY-132829
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GC4711
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Reactive Oxygen Species
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Cancer
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Rucosopasem manganese (GC4711) is a selective superoxide dismutase mimetic that converts superoxide to hydrogen peroxide. Rucosopasem manganese can be used for the research of cancer .
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- HY-109110
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GC-4419; M-40419
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Reactive Oxygen Species
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Inflammation/Immunology
Cancer
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Avasopasem manganese (GC4419; M-40419) is a potent superoxide dismutase mimetic that rapidly and specifically converts O2 *- to hydrogen peroxide (H2O2), arresting the initiation of this cascade. Avasopasem manganese can be used for the research of severe oral mucositis (SOM) and cancer .
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- HY-149234
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Monoamine Oxidase
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Neurological Disease
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MAO-B-IN-18 is a potent and selective MAO B inhibitor with IC50s of 52 nM and 14 μM for hMAO B and hMAO A, respectively. MAO-B-IN-18 enables promising cytoprotective effects against hydrogen peroxide insults in neuroblastoma and astrocytes cultures .
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- HY-126474
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Reactive Oxygen Species
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Inflammation/Immunology
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MitoB bromide is an exomarker of mitochondrial hydrogen peroxide. MitoB bromide is a mitochondria-targeted ratiometric probe, and can be used to measure levels of one major ROS, hydrogen peroxide, within living animals .
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- HY-N0525
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- HY-P4280
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- HY-132183
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Endogenous Metabolite
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Metabolic Disease
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Chloride peroxidase is a monomeric, heme-containing enzyme. Chloride peroxidase is capable of electrophilic chlorinations through the umpolung of chloride by oxidation with hydrogen peroxide .
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- HY-101859
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NucPE1
1 Publications Verification
Nuclear Peroxy Emerald 1
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Reactive Oxygen Species
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Others
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NucPE1 (Nuclear Peroxy Emerald 1) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
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- HY-121026
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- HY-15914
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DCHBS
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Fluorescent Dye
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Others
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DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.
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- HY-100111
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GLX351322
Maximum Cited Publications
27 Publications Verification
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NADPH Oxidase
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Metabolic Disease
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GLX351322 is an inhibitor of NADPH oxidase 4 (Nox4), and inhibits hydrogen peroxide production from NOX4-overexpressing cells with an IC50 of 5 μM.
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- HY-D0169A
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Phenolsulfonephthalein sodium salt
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Fluorescent Dye
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Others
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Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .
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- HY-114740
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- HY-134757
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Others
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Others
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Lactate oxidase (EC 1.13.12.4) belongs to a group of FMN-dependent enzymes and they catalyze a conversion of lactate to pyruvate with a release of hydrogen peroxide. Lactate oxidase can be used in the detection of Lactate .
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- HY-N8453
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Methyl 3,5-dicaffeoyl quinic acid
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p38 MAPK
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Neurological Disease
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Macranthoin G is an inhibitor of p38 MAPK. Macranthoin G protects the cytotoxicity induced by Aβ or hydrogen peroxide in neuronal cells by downregulating p38 MAPK. Macranthoin G can used in study Alzheimer’s Disease .
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- HY-P2833
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GSH-Px; EC 1.11.1.9
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Glutathione Peroxidase
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Others
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Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .
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- HY-N8713
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Reactive Oxygen Species
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Others
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4-Methyl-6-phenyl-2H-pyranone can be used for the synthesis of N-hydroxypyridone derivatives, which can protect astrocytes against hydrogen peroxide-induced toxicity via improved mitochondrial functionality .
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- HY-132178
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Endogenous Metabolite
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Metabolic Disease
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Cytochrome P450 is a family of monooxygenase enzymes that catalyzes the conversion of fatty acids to terminal alkenes using hydrogen peroxide as a cosubstrate. Cytochrome P450 as membrane-bound hemoproteins, plays important roles in the detoxification of drugs, cellular metabolism, and homeostasis .
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- HY-D0169
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Phenolsulfonephthalein
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Fluorescent Dye
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Others
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Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .
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-
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- HY-P2910
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GOase
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Endogenous Metabolite
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Others
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Galactose Oxidase, Dactylium dendroides (GOase) from fungus is often used in biochemical studies. Galactose oxidase is a type II copper metalloenzyme, and it containing a single polypeptide. Galactose oxidase catalyzes two-electron oxidation of primary alcohols to their corresponding aldehydes, coupling with the reduction of dioxygen to hydrogen peroxide .
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- HY-155454
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Others
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Inflammation/Immunology
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TATP hapten is a hapten made from acetone, hydrogen peroxide, and 7-oxo octanoic acid. TATP hapten coupled with bovine serum albumin can raise an immune response against TATP. TATP hapten can coupled directly to BSA and HRP via N-hydroxysuccinimide chemistry to produce haptenated proteins .
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- HY-E70074
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Monoamine Oxidase
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Neurological Disease
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Monoamine oxidase (EC 1.4.3.4) is an enzyme composed of different polypeptides. Monoamine oxidation catalyzes the oxidative deamination of various biological amines in brain and peripheral tissues by producing hydrogen peroxide. Monoamine oxidase plays an important role in maintaining the regulation of synaptic transmission, emotional behavior and other brain functions .
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- HY-15929
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2,4,6-Tribromo-3-hydroxybenzoic acid
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Biochemical Assay Reagents
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Others
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The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) which reacts with hydrogen peroxide and 4-aminophenazone to produce a quinone-imine dye with a greater molar absorptivity than that produced with phenol.
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- HY-N0828
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|
Autophagy
|
Inflammation/Immunology
Cancer
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Pterostilbene is a stilbenoid isolated from blueberries and Pterocarpus marsupium . Shows anti-oxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic and anti-obesity properties . Pterostilbene blocks ROS production , also exhibits inhibitory activity against various free radicals such as DPPH, ABTS, hydroxyl, superoxide and hydrogen peroxide .
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- HY-P2902
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|
Endogenous Metabolite
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Cancer
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Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
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- HY-W011664
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DPBF
|
Fluorescent Dye
Reactive Oxygen Species
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Others
|
1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
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- HY-D0945
-
|
Fluorescent Dye
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Others
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Xylene Cyanol FF is an acid triphenylmethane dye. Xylene Cyanol FF can be used for histochemical staining of hemoglobin peroxidase or as a tracking dye for DNA sequencing in electrophoresis. Xylene Cyanol FF will be catalyzed by Fe and Al to accelerate oxidation under the addition of double oxidant hydrogen peroxide and potassium periodate. Xylene Cyanol FF thus enables the spectrophotometric determination of Fe and Al in the solution to be tested .
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- HY-103385
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NO-Aspirin
|
Apoptosis
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Inflammation/Immunology
Cancer
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NCX4040 (NO-Aspirin), a non-steroidal anti-inflammatory drug (NSAID), is a nitric oxide (NO) releasing form of Aspirin. NCX4040 induces apoptosis in PC3 metastatic prostate cancer cells. NCX4040 has anti-inflammatory and anti-cancer effects .
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- HY-N11526
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Others
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Inflammation/Immunology
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3-Hydroxy-2-(palmitoyloxy)propyl stearat is a non-volatile compound. 3-Hydroxy-2-(palmitoyloxy)propyl stearat can be isolated from less polar fractions of the brown macroalga Fucus virsoides J. Agardh. This part of the substance has a good ability to scavenge free radicals and has a protective effect on the oxidative stress induced by hydrogen peroxide in zebrafish embryos .
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- HY-D1157
-
|
Fluorescent Dye
Reactive Oxygen Species
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Others
|
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
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- HY-P1997
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Desferrichrome; DFC; N-Desferriferrichrome
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Biochemical Assay Reagents
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Others
|
Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
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- HY-106784A
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Others
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Neurological Disease
|
(E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
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- HY-D1840
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|
Biochemical Assay Reagents
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Others
|
Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .
|
-
Cat. No. |
Product Name |
Type |
-
- HY-W402148
-
|
Fluorescent Dyes/Probes
|
10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate, a phenyl ester of acridinium esters, is a fluorescent dye that produces chemiluminescent under neutral conditions. 10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate can be used for the measurement of hydrogen peroxide .
|
-
- HY-101859
-
NucPE1
1 Publications Verification
Nuclear Peroxy Emerald 1
|
Fluorescent Dyes/Probes
|
NucPE1 (Nuclear Peroxy Emerald 1) is a nuclear-localized fluorescent hydrogen peroxide that is specifically localized to cellular nuclei without appended targeting moieties.
|
-
- HY-15914
-
DCHBS
|
Chromogenic Substrates
|
DHBS is Used in conjunction with 4-aminoantipyrine (4-AAP) and hydrogen peroxide (H2O2) for chromogenic quantitation of peroxidase in coupled enzymatic reactions.
|
-
- HY-D0169A
-
Phenolsulfonephthalein sodium salt
|
Dyes
|
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .
|
-
- HY-D0169
-
Phenolsulfonephthalein
|
Dyes
|
Phenol red (Phenolsulfonephthalein) is a pH indicator dye, relying on a distinct color change from pink to yellow in case of a positive reaction .
|
-
- HY-W011664
-
DPBF
|
Fluorescent Dyes/Probes
|
1,3-Diphenylisobenzofuran (DPBF) has been developed as a selective probe for the detection and quantitative determination of hydrogen peroxide in samples containing different reactive nitrogen and oxygen species (RNOS). DPBF is a fluorescent probe which, for almost 20 years, was believed to react in a highly specific manner toward some reactive oxygen species such as singlet oxygen and hydroxy, alkyloxy or alkylperoxy radicals .
|
-
- HY-D0945
-
|
Dyes
|
Xylene Cyanol FF is an acid triphenylmethane dye. Xylene Cyanol FF can be used for histochemical staining of hemoglobin peroxidase or as a tracking dye for DNA sequencing in electrophoresis. Xylene Cyanol FF will be catalyzed by Fe and Al to accelerate oxidation under the addition of double oxidant hydrogen peroxide and potassium periodate. Xylene Cyanol FF thus enables the spectrophotometric determination of Fe and Al in the solution to be tested .
|
-
- HY-D1157
-
|
Fluorescent Dyes/Probes
|
HKPerox-2 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively .
|
-
- HY-D1840
-
|
Dyes
|
Tyramide Amplification Buffer is a ready-to-use buffer primarily intended for immunostaining of cells and tissues by the technique of tyramide signal amplification (TSA). TSA Technology is based on a tyrosinase labeling system that reacts a tyrosine-labeled antibody with a fluorescently labeled tyramide using peroxidase to form a highly amplified fluorescent signal. For example, horseradish peroxidase (HRP) can catalyze the reaction of tyrosine and hydrogen peroxide under milder conditions to generate epoxy groups. Epoxy groups promote the binding of tyramide to adjacent amino acids to form fluorescently labeled products .
|
Cat. No. |
Product Name |
Type |
-
- HY-15929
-
2,4,6-Tribromo-3-hydroxybenzoic acid
|
Biochemical Assay Reagents
|
The Boehringer Mannheim cholesterol esterase/cholesterol oxidase/peroxidase/3,4-dichlorophenol kinetic reagent was modified by the inclusion of TBHBA (2,4,6-Tribromo-3-hydroxybenzoic acid) which reacts with hydrogen peroxide and 4-aminophenazone to produce a quinone-imine dye with a greater molar absorptivity than that produced with phenol.
|
-
- HY-P2902
-
|
Biochemical Assay Reagents
|
Glucose oxidase is used in the food and beverage industry as a preservative and stabilizer and is commonly derived from the fungus Aspergillus niger. Glucose oxidase can react with intracellular glucose and oxygen (O2) to produce hydrogen peroxide (H2O2) and gluconic acid, which can cut off the nutrition source of cancer cells and consequently inhibit their proliferation .
|
-
- HY-D0945
-
|
Dyes
|
Xylene Cyanol FF is an acid triphenylmethane dye. Xylene Cyanol FF can be used for histochemical staining of hemoglobin peroxidase or as a tracking dye for DNA sequencing in electrophoresis. Xylene Cyanol FF will be catalyzed by Fe and Al to accelerate oxidation under the addition of double oxidant hydrogen peroxide and potassium periodate. Xylene Cyanol FF thus enables the spectrophotometric determination of Fe and Al in the solution to be tested .
|
-
- HY-E70009
-
ACO
|
Biochemical Assay Reagents
|
Acyl-CoA oxidase (ACO) catalyses the first and rate-determining step of the peroxisomal beta-oxidation of fatty acids and a major producer of hydrogen peroxide (H2O2) .
|
-
- HY-P2833
-
GSH-Px; EC 1.11.1.9
|
Biochemical Assay Reagents
|
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9) belongs to the peroxidase family and is commonly used in biochemical research. Glutathione Peroxidase can catalyze reduced glutathione (GSH) to form a disulfide bridge with another glutathione molecule, convert it into oxidized glutathione (GSSG), and react with hydrogen peroxide or lipid peroxide reaction, reducing it to H2O. Glutathione Peroxidase is an effective antioxidant against oxidative stress .
|
Cat. No. |
Product Name |
Target |
Research Area |
-
- HY-P4280
-
-
- HY-P1997
-
Desferrichrome; DFC; N-Desferriferrichrome
|
Biochemical Assay Reagents
|
Others
|
Ferrichrome is a hydroxamate siderophore produced by various fungi, including U. sphaerogena, that facilitates iron chelation and uptake by these organisms. It can be used as a heterosiderophore by bacteria, including Pseudomonas aeruginosa and Vibrio parahaemolyticus. Ferrichrome (0.8 μM) inhibits concanavalin A-induced proliferation of mouse spleen monocytes and reduces the number of concanavalin A-stimulated CD4+ T cells expressing IL-2 receptor. It also inhibits the heme-catalyzed oxidation of LDL by hydrogen peroxide in a concentration-dependent manner.
|
Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
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